Gynecological Line:

Clinical Line:

Pediatric Line:

Products

Clinical Line

Trane®

Oral hypoglycemic of proven efficacy

Maximum efficacy in diabetes type 2

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Wide safety

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Patient information

Formula:
Formula
Trane® Formula each grooved tablet contains 125 mg de chlorpropamide.
Trane®250 Formula each grooved tablet contains chlorpropamide 250 mg.


Therapeutical Action :
Therapeutical action:
Oral hypoglycemic of the sulfonylurea group


Indications:
Indications:
Diabetes mellitus in the adult, stable, from mild to moderate, uncomplicated, non-ketosic, that cannot be controlled with diet alone.
Contraindications: Insulin-dependent diabetes mellitus (juvenile form) severe or instable diabetes. Diabetes complicated with ketosis and acidosis. Diabetic Coma. Surgery and severe trauma. Pregnancy. Severe hepatic and/or renal failure. Hypersensibility to the active principle. In case of severe infection, high fever, hepatic or renal dysfunction, hypophysis and/or suprarenal failure, the relation risk-benefit should be assessed.


Posology:
Posology:
Suggested dosage: initial dose for adults: 100 mg to 250 mg of chlorpropamide in an only intake generally after breakfast. In older patients, treatment should never start with doses of more that 125 mg of chlorpropamide per day.
Adjustments: One week after starting treatment, the initial dose should be increased or decreased with variations of 50 mg to 125 mg per week until achieving control of diabetes.


Presentation:
Presentation:
Trane® each package contains 20 and 50 grooved tablets.
Trane® 250: each package contains 20 and 60 grooved tablets